Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM0XQZO)

Drug Name

PMID22795084C1 Drug Info

Synonyms

compound 1 (allosteric); GTPL7032; MolPort-019-906-830; BDBM50427768; ZINC75343937; AKOS022046525; MCULE-7514836384

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

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Drug(s) Targeting Protein arginine methyltransferase 3 (PRMT3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
SGC707	DMGINBT	Discovery agent	N.A.	Investigative	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Protein arginine methyltransferase 3 (PRMT3)	TTL4XSQ	ANM3_HUMAN	Inhibitor	[1]

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References

1	An allosteric inhibitor of protein arginine methyltransferase 3. Structure. 2012 Aug 8;20(8):1425-35.
2	A potent, selective and cell-active allosteric inhibitor of protein arginine methyltransferase (PRMT3). Angew Chem Int Ed Engl. 2015 Apr 20;54(17):5166-70.