Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM15VBJ)

Drug Name

Artemisone Drug Info

Synonyms

Artemifone; Artemisone, Medicines For Malaria Venture; MMV-00/1007; Artemisinin derviative, Bayer/WHO/Hong Kong University; Artemisone, Bayer/WHO/Hong Kong University; Semi-synthetic endoperoxide, Bayer/WHO/Hong Kong University

Indication

Disease Entry	ICD 11	Status	REF
Malaria	1F40-1F45	Phase 2/3	[1]

Cross-matching ID

PubChem CID: 11531457
CAS Number: CAS 255730-18-8
TTD Drug ID: DM15VBJ

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Beta-hematin formation (BHF)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Arteether	DMQLX7O	Malaria	1F40-1F45	Approved	[3]
------------------------------------------------------------------------------------

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Beta-hematin formation (BHF)	TT9X7H4	NOUNIPROTAC	Modulator	[2]

------------------------------------------------------------------------------------

References

1	ClinicalTrials.gov (NCT00936767) Artemisone for the Treatment of Uncomplicated Falciparum Malaria in Western Cambodia. U.S. National Institutes of Health.
2	Anticancer Properties of Distinct Antimalarial Drug Classes. PLoS One. 2013; 8(12): e82962.
3	Lack of association of the S769N mutation in Plasmodium falciparum SERCA (PfATP6) with resistance to artemisinins. Antimicrob Agents Chemother. 2012 May;56(5):2546-52.