Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM25BNZ)

Drug Name
PMID27998201-Compound-24 Drug Info
Indication
Disease Entry ICD 11 Status REF
Glioma 2A00.0 Patented [1]
Meningioma tumour 2A01 Patented [1]
Cross-matching ID
PubChem CID
6431125
TTD Drug ID
DM25BNZ

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Patented Agent(s)
Preclinical Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Cathepsin B (CTSB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
PMID27998201-Compound-12 DM8QZNC Bone cancer 2B5Z Patented [1]
PMID27998201-Compound-5 DMVZ0ND Chronic obstructive pulmonary disease CA22 Patented [1]
PMID27998201-Compound-9 DM1JOZN Rheumatoid arthritis FA20 Patented [1]
PMID27998201-Compound-17 DMAZVHJ Hair loss ED70 Patented [1]
PMID27998201-Compound-11 DMTV5NU Metastatic cancer 2D50-2E2Z Patented [1]
PMID27998201-Compound-2 DMMAE3C Alzheimer disease 8A20 Patented [1]
PMID27998201-Compound-22 DMS9QA7 Alzheimer disease 8A20 Patented [1]
PMID27998201-Compound-13 DMZHIM8 Hepatic fibrosis DB93.0 Patented [1]
Dimethoxybenzylidene-2-thio-imidazole-4-one derivative 1 DMZ4B3W Cerebral ischemia 8B11 Patented [1]
L-006235-1 DMMEH12 Osteoarthritis FA00-FA05 Preclinical [2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Cathepsin B (CTSB) TTF2LRI CATB_HUMAN Inhibitor [1]

References

1 Cathepsin B and L inhibitors: a patent review (2010 - present).Expert Opin Ther Pat. 2017 Jun;27(6):643-656.
2 Lysosomotropism of basic cathepsin K inhibitors contributes to increased cellular potencies against off-target cathepsins and reduced functional se... J Med Chem. 2005 Dec 1;48(24):7535-43.