Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM2POGY)

Drug Name

AMG 509 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Prostate cancer	2C82.0	Phase 1	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Metalloreductase STEAP1 (STEAP1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
RG7450	DM1NHEA	Prostate cancer	2C82.0	Phase 1	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Metalloreductase STEAP1 (STEAP1)	TT9E64S	STEA1_HUMAN	Inhibitor	[2]

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References

1	ClinicalTrials.gov (NCT04221542) Study of AMG 509 in Subjects With Metastatic Castration-Resistant Prostate Cancer. U.S. National Institutes of Health.
2	Clinical pipeline report, company report or official report of Amgen.
3	Marine-Sourced Anti-Cancer and Cancer Pain Control Agents in Clinical and Late Preclinical Development. Mar Drugs. 2014 January; 12(1): 255-278.