Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM2USXP)

Drug Name
Remlarsen Drug Info
Indication
Disease Entry ICD 11 Status REF
Keloid EE60 Phase 2 [1]
Cross-matching ID
TTD Drug ID
DM2USXP

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
microRNA hsa-miR-29b (MIR29b) TTO60BY NOUNIPROTAC Replacement [2]

References

1 ClinicalTrials.gov (NCT03601052) Efficacy, Safety, and Tolerability of Remlarsen (MRG-201) Following Intradermal Injection in Subjects With a History of Keloids. U.S. National Institutes of Health.
2 A MicroRNA-29 Mimic (Remlarsen) Represses Extracellular Matrix Expression and Fibroplasia in the Skin. J Invest Dermatol. 2019 May;139(5):1073-1081.