Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM37CX4)

Drug Name
IC14 Drug Info
Synonyms CD14 antibody
Indication
Disease Entry ICD 11 Status REF
Coronavirus Disease 2019 (COVID-19) 1D6Y Phase 2 [1]
Sepsis 1G40-1G41 Phase 2 [2]
Therapeutic Class
Antiviral Agents
Cross-matching ID
TTD Drug ID
DM37CX4

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
HUAMN monocyte differentiation antigen CD14 (CD14) TTCLGZ8 CD14_HUMAN Inhibitor [1]
Monocyte differentiation antigen CD14 (CD14) TT6I7DC CD14_HUMAN Not Available [3]

References

1 IC14 (Anti-CD14) Treatment in Patients With SARS-CoV-2 (COVID-19)
2 ClinicalTrials.gov (NCT00233207) IC14 Antibodies to Treat Individuals With Acute Lung Injury. U.S. National Institutes of Health.
3 IC14, a CD14 specific monoclonal antibody, is a potential treatment for patients with severe sepsis. J Endotoxin Res. 2001;7(4):310-4.