General Information of Drug (ID: DM3BDHN)

Drug Name
US10081632, Compound 25 Drug Info
Synonyms
SCHEMBL19252896; BDBM286094; US10081632, Compound 25; Synthesis of (R) inverted question markN-(1-(4-aminobenzyl)-1H-pyrazol-4-yl)-9-methyl-6-oxo-6,7,8,9-tetrahydropyrido[3',2':4,5]pyrrolo[1,2-a]pyrazine-2-carboxamide hydrochloride salt
Cross-matching ID
PubChem CID
130338820
TTD Drug ID
DM3BDHN

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Patented Agent(s)
Preclinical Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
CID 138805970 DMINXMY N. A. N. A. Patented [1]
BI-D1870 DMK3SAF Chronic lymphocytic leukaemia 2A82.0 Preclinical [2]
PMID22564207C25b DMBMYKQ Discovery agent N.A. Investigative [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Ribosomal protein S6 kinase alpha-6 (RSK6) TT3KYWB KS6A6_HUMAN Inhibitor [1]

References

1 Substituted tetrahydropyrido[3,2:4,5]pyrrolo[1,2-a]pyrazine-2-carboxamides as RSK inhibitors. US9771366.
2 BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo. Biochem J. 2007 Jan 1;401(1):29-38.
3 Discovery of an orally efficacious inhibitor of anaplastic lymphoma kinase. J Med Chem. 2012 May 24;55(10):4580-93.