Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM3ISKB)

Drug Name

PIRODAVIR Drug Info

Synonyms

Pirodavir < Rec INN; R-77975; 4-[2-[1-(6-Methyl-3-pyridazinyl)-4-piperidinyl]ethoxy]benzoic acid ethyl ester

Indication

Disease Entry	ICD 11	Status	REF
Virus infection	1A24-1D9Z	Discontinued in Phase 2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

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Drug(s) Targeting Rhinovirus Capsid protein (HRV VP)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
BTA-798	DMDWP0U	Rhinovirus infection	CA07	Phase 2	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Rhinovirus Capsid protein (HRV VP)	TT8R3VP	POLG_HRV1A	Modulator	[2]

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References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001224)
2	In vitro activity of expanded-spectrum pyridazinyl oxime ethers related to pirodavir: novel capsid-binding inhibitors with potent antipicornavirus activity. Antimicrob Agents Chemother. 2004 May;48(5):1766-72.
3	Combating enterovirus replication: state-of-the-art on antiviral research. Biochem Pharmacol. 2012 Jan 15;83(2):185-92.