General Information of Drug (ID: DM47L9Q)

Drug Name
Mycophenolic acid/nucleotide derivative 12 Drug Info
Synonyms PMID28074661-Compound-US20087427636c63
Cross-matching ID
TTD Drug ID
DM47L9Q

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Mercaptopurine DMTM2IK Acute lymphoblastic leukaemia 2A85 Approved [2]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [3]
Merimepodib DM0HS92 Breast cancer 2C60-2C65 Approved [4]
Tiazofurin DM5JWV9 Solid tumour/cancer 2A00-2F9Z Approved [5]
Mizoribine DMW6F0S Transplant rejection NE84 Approved [4]
Viramidine DMJFNR9 Hepatitis C virus infection 1E51.1 Phase 3 [6]
VX-944 DME321B Solid tumour/cancer 2A00-2F9Z Phase 2 [1]
VX-148 DML32R8 Psoriasis vulgaris EA90 Patented [7]
PMID28074661-Compound-US20100022547C81 DMM9E1U N. A. N. A. Patented [1]
PMID28074661-Compound-US20120264760C80 DM75QVW N. A. N. A. Patented [1]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Inosine-5'-monophosphate dehydrogenase 1 (IMPDH1) TTL7C8Q IMDH1_HUMAN Inhibitor [1]

References

1 Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitors: a patent and scientific literature review (2002-2016).Expert Opin Ther Pat. 2017 Jun;27(6):677-690.
2 Clinical pharmacology and pharmacogenetics of thiopurines. Eur J Clin Pharmacol. 2008 Aug;64(8):753-67.
3 Treating HCV with ribavirin analogues and ribavirin-like molecules. J Antimicrob Chemother. 2006 Jan;57(1):8-13.
4 VX-497: a novel, selective IMPDH inhibitor and immunosuppressive agent. J Pharm Sci. 2001 May;90(5):625-37.
5 In vitro and in vivo antiproliferative activity of IPCAR, a new pyrazole nucleoside analog. Anticancer Res. 1998 Jul-Aug;18(4A):2623-30.
6 Antiviral agents active against influenza A viruses. Nat Rev Drug Discov. 2006 Dec;5(12):1015-25.
7 Characterization of pharmacological efficacy of VX-148, a new, potent immunosuppressive inosine 5'-monophosphate dehydrogenase inhibitor. J Pharmacol Exp Ther. 2002 Sep;302(3):1272-7.