Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM4EFRL)

Drug Name	PMID27977313-Compound-48 Drug Info
Cross-matching ID	PubChem CID 25193001 TTD Drug ID DM4EFRL

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Patented Agent(s)

Download the Complete Related Drug List

Drug(s) Targeting Cytoplasmic thioredoxin reductase (TXNRD1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fotemustine	DMV62ED	Solid tumour/cancer	2A00-2F9Z	Approved	[2]
Spermidine	DMVJNFI	Plaque psoriasis	EA90.0	Phase 3	[2]
Golden phosphorous acetyletic compound 2	DMYJ15A	N. A.	N. A.	Patented	[1]
Terpyridineplatinum(II) complexe 3	DM54EFD	N. A.	N. A.	Patented	[1]
Terpyridineplatinum(II) complexe 4	DMOV86T	N. A.	N. A.	Patented	[1]
Golden phosphorous acetyletic compound 1	DMVAKUI	N. A.	N. A.	Patented	[1]
Acyl oxymethyl acrylamide ester derivative 1	DMXTUE1	N. A.	N. A.	Patented	[1]
PMID27977313-Compound-18	DMIA3GH	N. A.	N. A.	Patented	[1]
Triazole gold complexe 1	DMCWES7	N. A.	N. A.	Patented	[1]
4-aryl quinol derivative 2	DM7TW5Z	N. A.	N. A.	Patented	[1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Cytoplasmic thioredoxin reductase (TXNRD1)	TTR7UJ3	TRXR1_HUMAN	Inhibitor	[1]

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References

1	Thioredoxin reductase inhibitors: a patent review.Expert Opin Ther Pat. 2017 May;27(5):547-556.
2	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.