Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM4VZCW)

Drug Name

Polyinosinic:polycytidylic acid Drug Info

Synonyms

NSC-120,949; PI:C; Poly 1-poly-c; Poly C poly I; Poly I:poly C; Poly IC; Poly rI:poly rC; Poly(I).poly(C); Poly(I).poly(C) complex; Poly(I:C); Poly(rI)-poly(rC); Poly(rI).(rC); Poly(rI).poly(rC); Poly(rI:rC); Polycytid; Polyinosinic acid.polycytidylic acid; Polyinosinic-polycyticylic acid complex; Polyriboinosinic acid:polyribocytidylic acid; polyinosine-polycytosine

Indication

Disease Entry	ICD 11	Status	REF
Middle East Respiratory Syndrome (MERS)	1D64	Investigative	[1]

Therapeutic Class

Antiviral Agents

Cross-matching ID

PubChem CID: 135618150
TTD Drug ID: DM4VZCW

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Download the Complete Related Drug List

Drug(s) Targeting HUMAN toll-like receptor 3 (TLR3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Rintatolimod	DMSDZ8U	Chronic fatigue syndrome	8E49	Phase 1/2 Trial	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
HUMAN toll-like receptor 3 (TLR3)	TT1CN09	TLR3_HUMAN	Agonist	[1]

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References

1	Middle East Respiratory Syndrome Coronavirus (MERS-CoV): Infection, Immunological Response, and Vaccine Development. J Immunol Res. 2019 Apr 7;2019:6491738. doi: 10.1155/2019/6491738.
2	Efficacy of rintatolimod in the treatment of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME). Expert Rev Clin Pharmacol. 2016 Jun;9(6):755-70.