General Information of Drug (ID: DM4WXD2)

Drug Name
[2-Phenylacetophenone]thiosemicarbazone Drug Info
Synonyms CHEMBL1269810; [2-Phenylacetophenone]thiosemicarbazone
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
52945875
TTD Drug ID
DM4WXD2

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Patented Agent(s)
Drug(s) Targeting Cathepsin L (CTSL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
KGP94 DM2NZ6K Coagulation defect 3B10.0 Clinical trial [1]
PMID27998201-Compound-12 DM8QZNC Bone cancer 2B5Z Patented [2]
PMID27998201-Compound-5 DMVZ0ND Chronic obstructive pulmonary disease CA22 Patented [2]
PMID27998201-Compound-9 DM1JOZN Rheumatoid arthritis FA20 Patented [2]
PMID25399719-Compound-17 DMRXKJZ N. A. N. A. Patented [3]
PMID27998201-Compound-17 DMAZVHJ Hair loss ED70 Patented [2]
Phenylalanine derivative 1 DMVYP8K Glioma 2A00.0 Patented [2]
PMID27998201-Compound-7 DMU4QYR Abdominal aortic aneurysm BD50.4 Patented [2]
PMID27998201-Compound-6 DM0LGTY N. A. N. A. Patented [2]
PMID27998201-Compound-1 DM5QH4C Coronavirus infection 1D92 Patented [2]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Cathepsin L (CTSL) TT36ETB CATL1_HUMAN Inhibitor [1]

References

1 Functionalized benzophenone, thiophene, pyridine, and fluorene thiosemicarbazone derivatives as inhibitors of cathepsin L. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6610-5.
2 Cathepsin B and L inhibitors: a patent review (2010 - present).Expert Opin Ther Pat. 2017 Jun;27(6):643-656.
3 An updated patent review of calpain inhibitors (2012 - 2014).Expert Opin Ther Pat. 2015 Jan;25(1):17-31.