Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM4YGWA)

Drug Name

Esonarimod Drug Info

Synonyms

Sonatimod; KE-298; KE-749; KE-758; NE-298; (R)-KE-298; (S)-KE-298

Indication

Disease Entry	ICD 11	Status	REF
Arthritis	FA20	Phase 3	[1]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
TNF-alpha/IL-1 beta production (TNFA/IL1B produ)	TTGD6BY	NOUNIPROTAC	Modulator	[1]

------------------------------------------------------------------------------------

References

1	KE-758, an active metabolite of the new anti-rheumatic drug KE-298, suppresses production of tumor necrosis factor-alpha and interleukin-1 beta in THP-1, a human monocyte cell line. Drugs Exp Clin Res. 2002;28(5):197-205.