Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM6J2UZ)

Drug Name
MCC950 Drug Info
Synonyms
MCC950; 210826-40-7; MCC-950; CP-456773; CHEMBL3183703; N-[[(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-2-furansulfonamide; MCC 950; DSSTox_RID_82252; DSSTox_CID_27301; DSSTox_GSID_47301; SCHEMBL6521858; GTPL8228; DTXSID2047301; MolPort-042-579-517; EX-A1052; BCP15729; Tox21_300462; BDBM50155926; ZINC34025113; AKOS030238802; SB19010; NCGC00254269-01; NCGC00248064-01; HY-12815; CAS-210826-40-7; 1-[4-(1-Hydroxy-1-methylethyl)-2-furylsulfonyl]-3-[(1,2,3,5,6,7-hexahydro-s-indacene)-4-yl]urea
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
9910393
ChEBI ID
CHEMBL3183703
CAS Number
CAS 210826-40-7
TTD Drug ID
DM6J2UZ

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Caterpiller protein 1.1 (NLRP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dapansutrile DM7IH48 Acute gout flare FA25.0 Phase 2 [2]
BMS-986299 DMTMUWJ Solid tumour/cancer 2A00-2F9Z Phase 1 [3]
Selnoflast DM4NKNK Inflammation 1A00-CA43.1 Phase 1 [4]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Caterpiller protein 1.1 (NLRP3) TT4EN8X NLRP3_HUMAN Inhibitor [1]

References

1 A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases. Nat Med. 2015 Mar;21(3):248-55.
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 National Cancer Institute Drug Dictionary (drug name BMS-986299).
4 Clinical pipeline report, company report or official report of Roche