Details of the Drug-Related molecule(s) Interaction Atlas

SJA-6017 Drug Info

Calpain Inhibitor VI; SJA-6017; SJA6017; N-(4-Fluorophenylsulfonyl)-L-Valyl-L-Leucinal; CHEMBL288365; SCHEMBL1907361; ZINC1544687; BDBM50114340; J-012283; (S)-2-(4-fluorophenylsulfonamido)-3-methyl-N-((S)-4-methyl-1-oxopentan-2-yl)butanamide; (S)-2-(4-Fluoro-benzenesulfonylamino)-N-((S)-1-formyl-3-methyl-butyl)-3-methyl-butyramide

Cross-matching ID

PubChem CID

9885817

CAS Number

CAS 190274-53-4

TTD Drug ID

DM6X430

General Information of Drug (ID: DM6X430)

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Patented Agent(s)

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Drug(s) Targeting Calpain-2 (CAPN2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ABT-957	DMB9N4J	Alzheimer disease	8A20	Phase 1	[2]
PMID25399719-Compound-17	DMRXKJZ	N. A.	N. A.	Patented	[3]
Epoxysuccinate derivative 9	DM49FU0	N. A.	N. A.	Patented	[3]
Epoxysuccinate derivative 4	DMCF6M8	N. A.	N. A.	Patented	[3]
Carboxamide derivative 7	DM8TQS4	N. A.	N. A.	Patented	[3]
Epoxysuccinate derivative 7	DMTSPVF	N. A.	N. A.	Patented	[3]
Carboxamide derivative 10	DM5WMO9	N. A.	N. A.	Patented	[3]
Carboxamide derivative 11	DM1DN94	N. A.	N. A.	Patented	[3]
Carboxamide derivative 8	DM6HI34	N. A.	N. A.	Patented	[3]
Epoxysuccinate derivative 10	DMYF39U	N. A.	N. A.	Patented	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	Synthesis, biological evaluation and molecular modelling of N-heterocyclic dipeptide aldehydes as selective calpain inhibitors. Bioorg Med Chem. 2008 Jul 15;16(14):6911-23.
2	Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
3	An updated patent review of calpain inhibitors (2012 - 2014).Expert Opin Ther Pat. 2015 Jan;25(1):17-31.