Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM76S3X)

Drug Name

ARO-HBV Drug Info

Synonyms

JNJ-3989

Indication

Disease Entry	ICD 11	Status	REF
Hepatitis B	1E51	Phase 1/2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

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Drug(s) Targeting Hepatitis B virus messenger RNA (HBV mRNA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ISIS-HBV	DM4RXDQ	Hepatitis B virus infection	1E51.0	Phase 2	[3]
AB-729	DM48DPS	Hepatitis B virus infection	1E51.0	Phase 2	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Hepatitis B virus messenger RNA (HBV mRNA)	TT43YWN	NOUNIPROTAC	Inhibitor	[2]

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References

1	ClinicalTrials.gov (NCT03365947) Study of ARO-HBV in Normal Adult Volunteers and Patients With Hepatitis B Virus (HBV). U.S. National Institutes of Health.
2	Clinical pipeline report, company report or official report of Arrowhead Pharmaceuticals.
3	Clinical pipeline report, company report or official report of ISIS Pharmaceuticals.
4	Clinical pipeline report, company report or official report of Arbutus Biopharma.