Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM7SMNJ)

Drug Name
NKTR-255 Drug Info
Indication
Disease Entry ICD 11 Status REF
Colorectal cancer 2B91.Z Phase 1/2 [1]
Head and neck cancer 2D42 Phase 1/2 [1]
Cross-matching ID
TTD Drug ID
DM7SMNJ

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Interleukin 15 receptor alpha (IL15RA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
ALT-803 DMK3U1X Acute myeloid leukaemia 2A60 Phase 2 [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Interleukin 15 receptor alpha (IL15RA) TTGN89I I15RA_HUMAN Agonist [2]

References

1 ClinicalTrials.gov (NCT04616196) Study of NKTR 255 in Combination With Cetuximab in Solid Tumors. U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of Nektar Therapeutics.
3 Efficacy and mechanism-of-action of a novel superagonist interleukin-15: interleukin-15 receptor alphaSu/Fc fusion complex in syngeneic murine models of multiple myeloma. Cancer Res. 2013 May 15;73(10):3075-86.