Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM7U458)

Drug Name

IDX-184 Drug Info

Synonyms

B-102; B-184; B-299; IDX-102; Next-generation nucleotide polymerase inhibitors (HCV infection), Idenix; Next-generation nucleotide polymerase inhibitors (hepatitis C virus infection), Idenix; 2'-methyl guanosine prodrug (hepatitis C virus infection), Idenix

Indication

Disease Entry	ICD 11	Status	REF
Hepatitis C virus infection	1E51.1	Phase 1/2	[1]

Cross-matching ID

PubChem CID: 135565589
CAS Number: CAS 1036915-08-8
TTD Drug ID: DM7U458

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Hepatitis C virus Non-structural 5 (HCV NS5)	TTE3PC9	NOUNIPROTAC	Inhibitor	[2]

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References

1	ClinicalTrials.gov (NCT00807001) Double-Blind, Dose-Escalation Study of IDX184 in Chronic Hepatitis C Treatment-Naive Subjects. U.S. National Institutes of Health.
2	Genotype and Subtype Profiling of PSI-7977 as a Nucleotide Inhibitor of Hepatitis C Virus. Antimicrob Agents Chemother. 2012 June; 56(6): 3359-3368.