Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM7XGJY)

Drug Name
T-506 Drug Info
Synonyms 2'-Deoxy-5-fluoro-3'-oleoyluridine 5'-[2-(trimethylammonio)ethyl]phosphate hydrate
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Discontinued in Phase 2 [1]
Cross-matching ID
PubChem CID
6441168
CAS Number
CAS 104884-43-7
TTD Drug ID
DM7XGJY

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting FK506-binding protein (FKBP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ascrolimus DMZF68E Psoriasis vulgaris EA90 Phase 2 [3]
FK-505 DMGROQP Hyperuricaemia 5C55.Y Phase 2 [4]
Timcodar dimesilate DMDJLX7 Solid tumour/cancer 2A00-2F9Z Phase 1/2 [5]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
FK506-binding protein (FKBP) TTFH2RS NOUNIPROTAC Modulator [2]

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002432)
2 EP patent application no. 0831812, Methods and compositions for stimulating neurite growth.
3 Mode of action of tacrolimus (FK506): molecular and cellular mechanisms. Ther Drug Monit. 1995 Dec;17(6):584-91.
4 Prevention of Cardiac Hypertrophy by Calcineurin Inhibition. Circulation Research. 1999; 84: 623-632.
5 Analysis of FK506, timcodar (VX-853) and FKBP51 and FKBP52 chaperones in control of glucocorticoid receptor activity and phosphorylation. Pharmacol Res Perspect. 2014 December; 2(6): e00076.