General Information of Drug (ID: DM9M5WV)

Drug Name
MRG-201 Drug Info
Indication
Disease Entry ICD 11 Status REF
Keloid EE60 Phase 2 [1]
Scleroderma 4A42 Phase 1 [2]
Cross-matching ID
TTD Drug ID
DM9M5WV

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Investigative Drug(s)
Clinical Trial Drug(s)
Drug(s) Targeting Collagen (CO)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Vitamin C DMXJ7O8 Adenocarcinoma 2D40 Approved [3]
Collagenase DMFJ2OG Dermal ulcers 1A36 Approved [4]
Clostridial collagenase DMWTBG8 Discovery agent N.A. Investigative [5]
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cobomarsen DMF4MX9 Cutaneous T-cell lymphoma 2B01 Phase 2 [6]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Collagen (CO) TTK982E NOUNIPROTAC Modulator [2]
microRNA hsa-miR-155 (MIR155) TT1GNRQ NOUNIPROTAC Modulator [2]

References

1 ClinicalTrials.gov (NCT03601052) Efficacy, Safety, and Tolerability of Remlarsen (MRG-201) Following Intradermal Injection in Subjects With a History of Keloids. U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 Effects of vitamin C on dark circles of the lower eyelids: quantitative evaluation using image analysis and echogram. Skin Res Technol. 2009 May;15(2):214-7.
4 Contact dermatitis with clostridiopeptidase A contained in Noruxol ointment. Contact Dermatitis. 2007 Jun;56(6):361-2.
5 Collagen as a clinical target: nonoperative treatment of Dupuytren's disease. J Hand Surg Am. 2002 Sep;27(5):788-98.
6 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)