Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMAH435)

Drug Name
Quinazoline derivative 11 Drug Info
Synonyms PMID26936077-Compound-22
Indication
Disease Entry ICD 11 Status REF
Chronic obstructive pulmonary disease CA22 Patented [1]
Cirrhosis DB93 Patented [1]
Gastrointestinal disease DE2Z Patented [1]
Multiple sclerosis 8A40 Patented [1]
Psoriasis vulgaris EA90 Patented [1]
Cross-matching ID
PubChem CID
60163203
TTD Drug ID
DMAH435

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting Proteinase activated receptor 2 (PAR2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
MEDI0618 DM7GNSY Osteoarthritis pain MG30.31 Phase 1 [2]
Imidazopyridazine derivative 8 DMF7NXJ Inflammation 1A00-CA43.1 Patented [1]
Piperazine urea derivative 4 DM3K7IM Inflammation 1A00-CA43.1 Patented [1]
Piperidine derivative 2 DMHXMB4 Inflammation 1A00-CA43.1 Patented [1]
Benzimidazole derivative 10 DML3PE4 N. A. N. A. Patented [1]
Benzothiazine-carboxamide compound 2 DMMP2RT Skin inflammation EF20.Y Patented [1]
Peptide analog 71 DMSEKZG N. A. N. A. Patented [1]
Amidine compound 3 DMV0QJ4 Inflammation 1A00-CA43.1 Patented [1]
Benzothiazine-carboxamide compound 4 DMSR918 Skin inflammation EF20.Y Patented [1]
PMID26936077-Compound-13 DMXK6LV Gastric ulcer DA60 Patented [1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Proteinase activated receptor 2 (PAR2) TTQR74A PAR2_HUMAN Antagonist [1]

References

1 Protease activated receptor 2 (PAR2) modulators: a patent review (2010-2015).Expert Opin Ther Pat. 2016;26(4):471-83.
2 Clinical pipeline report, company report or official report of AstraZeneca