Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMB19IO)

Drug Name
Ad-IL-12 DNA therapeutic Drug Info
Synonyms INXN-2001
Indication
Disease Entry ICD 11 Status REF
Melanoma 2C30 Phase 1/2 [1]
Recurrent glioblastoma 2A00.00 Phase 1 [2]
Cross-matching ID
TTD Drug ID
DMB19IO

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Interleukin-12 beta (IL12B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isoproterenol DMK7MEY Atrioventricular block Approved [4]
ABT-874 DMYHSO2 Plaque psoriasis EA90.0 Phase 3 [5]
EGEN-001 DM6L5TR Fallopian tube cancer 2C74 Phase 2 [6]
SFV IL-12 gene therapy DMVIWNK Breast cancer 2C60-2C65 Phase 2 [7]
NHS-IL 12 DMU6CQ7 Solid tumour/cancer 2A00-2F9Z Phase 1 [8]
PF-07261271 DM0K4WQ Inflammatory bowel disease DD72 Phase 1 [9]
⏷ Show the Full List of 6 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Interleukin-12 beta (IL12B) TTGW72V IL12B_HUMAN Modulator [3]

References

1 Clinical pipeline report, company report or official report of ZIOPHARM.
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 National Cancer Institute Drug Dictionary (drug id 710508).
4 A phase 1 study of AS1409, a novel antibody-cytokine fusion protein, in patients with malignant melanoma or renal cell carcinoma. Clin Cancer Res. 2011 Apr 1;17(7):1998-2005.
5 Briakinumab for the treatment of plaque psoriasis.BioDrugs.2012 Feb 1;26(1):9-20.
6 National Cancer Institute Drug Dictionary (drug id 454593).
7 Clinical pipeline report, company report or official report of Trademarkia.
8 The immunocytokine NHS-IL12 as a potential cancer therapeutic. Oncotarget. 2014 Apr 15;5(7):1869-84.
9 Clinical pipeline report, company report or official report of Pfizer