Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMBI2PH)

• Drug Name: ISIS 25563 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID: TTD Drug ID: DMBI2PH

Molecule-Related Drug Atlas

Drug(s) Targeting RhoA messenger RNA (RHOA mRNA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ISIS 25565	DMB0CJ4	Discovery agent	N.A.	Investigative	[1]
ISIS 25554	DM5PXN4	Discovery agent	N.A.	Investigative	[1]
ISIS 25566	DMUR2TH	Discovery agent	N.A.	Investigative	[1]
ISIS 25551	DM41B62	Discovery agent	N.A.	Investigative	[1]
ISIS 25567	DMX72T6	Discovery agent	N.A.	Investigative	[1]
ISIS 25547	DM4P15C	Discovery agent	N.A.	Investigative	[1]
ISIS 25552	DMO8IVA	Discovery agent	N.A.	Investigative	[1]
ISIS 25564	DMMZW8J	Discovery agent	N.A.	Investigative	[1]
ISIS 25549	DMWXQPG	Discovery agent	N.A.	Investigative	[1]
ISIS 25544	DMB9DWH	Discovery agent	N.A.	Investigative	[1]

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
RhoA messenger RNA (RHOA mRNA)	TTP2U16	RHOA_HUMAN	Not Available	[1]

References

• [1] US patent application no. 5,945,290, Antisense modulation of RhoA expression.