Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMBKO2W)

Drug Name
ATI-355 Drug Info
Synonyms Atinumab; Anti-Nogo-A mAbs, Novartis; Anti-Nogo-A monoclonal antibodies, Novartis; 11C7; 7B12
Indication
Disease Entry ICD 11 Status REF
Nerve injury ND56.4 Phase 1 [1]
Cross-matching ID
TTD Drug ID
DMBKO2W

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Reticulon-4 (RTN4) TT7GXMU RTN4_HUMAN Not Available [2]

References

1 ClinicalTrials.gov (NCT00406016) Acute Safety, Tolerability, Feasibility and Pharmacokinetics of Intrath. Administered ATI355 in Patients With Acute SCI. U.S. National Institutes of Health.
2 Limiting multiple sclerosis related axonopathy by blocking Nogo receptor and CRMP-2 phosphorylation. Brain. 2012 June; 135(6): 1794-1818.