Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMBVCLY)

Drug Name

3-chloro-N-(4-(phenyldiazenyl)phenyl)benzamide Drug Info

Synonyms

CHEMBL566920; 3-chloro-N-(4-(phenyldiazenyl)phenyl)benzamide; 3-chloro-N-[4-(phenyldiazenyl)phenyl]benzamide; AC1MEGAF; MLS000571688; CHEMBL1585037; MolPort-002-176-797; HMS2431J18; ZINC18006916; BDBM50303375; AKOS002249913; MCULE-8045658796; SMR000193697; 3-chloro-N-(4-phenyldiazenylphenyl)benzamide; ST50752429

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 2877914
TTD Drug ID: DMBVCLY

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Discontinued Drug(s)

Investigative Drug(s)

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Drug(s) Targeting Trypanosoma Cruzipain (Trypano CYSP)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
TRICLABENDAZOLE	DMPWGBR	Helminth infection	1F90.0	Approved	[2]
MANIDIPINE	DMJPGUA	N. A.	N. A.	Phase 3	[2]
L-755507	DMPWBNU	N. A.	N. A.	Terminated	[1]
GNF-PF-4478	DMCDU8K	Discovery agent	N.A.	Investigative	[3]
K-777	DMIFCMW	Discovery agent	N.A.	Investigative	[4]
WRR-99	DM8ZA6K	Discovery agent	N.A.	Investigative	[5]
Benzoyl-Arginine-Alanine-Methyl Ketone	DMC7TNF	Discovery agent	N.A.	Investigative	[5]
Vinylsulphones	DMNFVO7	Infection of P. falciparum	1F40	Investigative	[6]
WRR-112	DMP761U	Discovery agent	N.A.	Investigative	[5]
1-(3-Methoxy-benzyl)-5-methyl-1H-indole-2,3-dione	DM30M9H	Discovery agent	N.A.	Investigative	[7]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Trypanosoma Cruzipain (Trypano CYSP)	TTEAID7	CYSP_TRYCR	Inhibitor	[1]

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References

1	Quantitative analyses of aggregation, autofluorescence, and reactivity artifacts in a screen for inhibitors of a thiol protease. J Med Chem. 2010 Jan 14;53(1):37-51.
2	Colloid formation by drugs in simulated intestinal fluid. J Med Chem. 2010 May 27;53(10):4259-65.
3	Complementarity between a docking and a high-throughput screen in discovering new cruzain inhibitors. J Med Chem. 2010 Jul 8;53(13):4891-905.
4	Novel non-peptidic vinylsulfones targeting the S2 and S3 subsites of parasite cysteine proteases. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6218-21.
5	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
6	Opportunities and challenges in antiparasitic drug discovery. Nat Rev Drug Discov. 2005 Sep;4(9):727-40.
7	Synthesis and evaluation of isatins and thiosemicarbazone derivatives against cruzain, falcipain-2 and rhodesain. Bioorg Med Chem Lett. 2003 Oct 20;13(20):3527-30.