Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMC8O3Z)

Drug Name

7-AMINO-4-METHYL-CHROMEN-2-ONE Drug Info

Synonyms

7-Amino-4-methylcoumarin; 26093-31-2; Coumarin 120; 7-Amino-4-methyl-2H-chromen-2-one; 4-Methyl-7-aminocoumarin; 2H-1-Benzopyran-2-one, 7-amino-4-methyl-; Coumarin, 7-amino-4-methyl-; 7-AMINO-4-METHYL-CHROMEN-2-ONE; UNII-OCY3JCT44X; CCRIS 4961; 7-amino-4-methylchromen-2-one; EINECS 247-454-8; NSC 45796; OCY3JCT44X; 7-amino-4-methyl-coumarin; MLS000057660; AMC; CHEBI:51771; GLNDAGDHSLMOKX-UHFFFAOYSA-N; NSC45796; MFCD00006868; GEO-02697; SMR000067752; AK-34405; 7-amino-4-methyl-2H-1-Benzopyran-2-one; A-6591; A1-00199; J-100007

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 92249
ChEBI ID: CHEBI:51771
CAS Number: CAS 26093-31-2
TTD Drug ID: DMC8O3Z

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Rotamase A (PPIA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
L-Proline	DMKSTWR	Malnutrition	5B50-5B71	Approved	[2]
3-[3-(3-benzyloxy-pyridin-2-yl)-ureido]-benzamide	DM60YGF	Discovery agent	N.A.	Investigative	[3]
(3r)-1-Acetyl-3-Methylpiperidine	DM49YTN	Discovery agent	N.A.	Investigative	[4]
1-(3-benzyloxy-pyridin-2-yl)-3-phenyl-urea	DMDZAVU	Discovery agent	N.A.	Investigative	[3]
Ethyl Oxo(Piperidin-1-Yl)Acetate	DM9KF0H	Discovery agent	N.A.	Investigative	[1]
4-[3-(3-benzyloxy-pyridin-2-yl)-ureido]-benzamide	DMOPRQ7	Discovery agent	N.A.	Investigative	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Rotamase A (PPIA)	TTL2ADK	PPIA_HUMAN	Inhibitor	[1]

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References

1	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
2	Mechanistic insight into the role of transition-state stabilization in cyclophilin A. J Am Chem Soc. 2009 Jan 14;131(1):147-52.
3	Structure-based design, synthesis, and biological evaluation of novel inhibitors of human cyclophilin A. J Med Chem. 2006 Feb 9;49(3):900-10.
4	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.