Details of the Drug-Related molecule(s) Interaction Atlas

US8524917, 10 Drug Info

SCHEMBL291250; CHEMBL3651713; HYKLZEZGHJEJET-UHFFFAOYSA-N; BDBM101037; US8524917, 10; US8563594, 168; 1-benzyl-N-(3,4-difluorobenzyl)-6-ethoxy-2-isopropyl-1H-indole-3-carboxamide

Cross-matching ID

PubChem CID

25059487

TTD Drug ID

DMCJH4F

General Information of Drug (ID: DMCJH4F)

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Patented Agent(s)

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Drug(s) Targeting Sphingosine-1-phosphate receptor 3 (S1PR3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
US9522888, 575	DM6UXZK	N. A.	N. A.	Patented	[2]
US9617250, Example 1 Example 204 of D1	DM89LKQ	N. A.	N. A.	Patented	[3]
YYDJCLCSBYCSCO-UHFFFAOYSA-N	DMA91FM	N. A.	N. A.	Patented	[4]
US9216972, 61	DM7AHQE	N. A.	N. A.	Patented	[5]
US9670220, 77	DMZG1HO	N. A.	N. A.	Patented	[6]
US10179791, Compound 296	DMLZBRM	N. A.	N. A.	Patented	[7]
JCXGHZCWAHCYGY-UHFFFAOYSA-N	DMER7QX	N. A.	N. A.	Patented	[4]
US9216972, 67	DMXR5SZ	N. A.	N. A.	Patented	[5]
US10166249, Example 695	DMVMNP1	N. A.	N. A.	Patented	[8]
US9181182, 40	DM3QIF4	N. A.	N. A.	Patented	[9]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Sphingosine-1-phosphate receptor 3 (S1PR3)	TTDYP7I	S1PR3_HUMAN	Inhibitor	[1]

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References

1	6-substituted indole-3-carboxylic acid amide compounds having sphingosine-1-phosphate (S1P) receptor antagonist biological activity. US8524917.
2	Substituted bicyclic compounds. US9522888.
3	Pyridin-4-yl derivatives. US9617250.
4	6-amino-pyrimidine-4-carboxamide derivatives and related compounds which bind to the sphingosine 1-phosphate (S1P) receptor for the treatment of multiple sclerosis. US9150519.
5	Tricyclic heterocyclic compounds. US9216972.
6	Fused heterocyclic derivatives as S1P modulators. US9670220.
7	Spiro-cyclic amine derivatives as S1P modulators. US10179791.
8	Substituted bicyclic compounds. US10166249.
9	S1P receptors modulators. US9181182.