Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMCO0ZS)

Drug Name
Benzotriazole derivative 1 Drug Info
Synonyms PMID26560530-Compound-40
Cross-matching ID
PubChem CID
25023511
TTD Drug ID
DMCO0ZS

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting Tissue transglutaminase (TG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
ZED1227 DMDXEN5 Coeliac disease DA95 Phase 2 [2]
PMID26560530-Compound-13 DMKF26Z N. A. N. A. Patented [1]
PMID26560530-Compound-54 DM2X4R0 N. A. N. A. Patented [1]
Triazole derivative 1 DM9QB2S N. A. N. A. Patented [1]
Acyl piperidine derivative 3 DMIDUB4 N. A. N. A. Patented [1]
PMID26560530-Compound-14 DM52MIK N. A. N. A. Patented [1]
PMID26560530-Compound-1 DMSI7F2 N. A. N. A. Patented [1]
PMID26560530-Compound-3 DM92OT0 N. A. N. A. Patented [1]
PMID26560530-Compound-11 DMZ5UST N. A. N. A. Patented [1]
Chloroacetyl ester derivative 1 DMW4J0P N. A. N. A. Patented [1]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Tissue transglutaminase (TG2) TT2F4OL TGM2_HUMAN Inhibitor [1]

References

1 Transglutaminase inhibitors: a patent review.Expert Opin Ther Pat. 2016;26(1):49-63.
2 Features of ZED1227: The First-In-Class Tissue Transglutaminase Inhibitor Undergoing Clinical Evaluation for the Treatment of Celiac Disease. Cells. 2022 May 17;11(10):1667.