General Information of Drug (ID: DMCPKV9)

Drug Name
ISIS 134605 Drug Info
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
TTD Drug ID
DMCPKV9

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isoquinoline-1,3,4(2H)-trione DMT4RI2 Discovery agent N.A. Investigative [2]
ISIS 134602 DMDS4BP Discovery agent N.A. Investigative [1]
ISIS 134583 DM0HWRN Discovery agent N.A. Investigative [1]
ISIS 134566 DMCM2S4 Discovery agent N.A. Investigative [1]
ISIS 134524 DMFCOA5 Discovery agent N.A. Investigative [1]
ISIS 134532 DMRFMVL Discovery agent N.A. Investigative [1]
Ac-VEID-CHO DMWOYCZ Discovery agent N.A. Investigative [3]
ISIS 134609 DMYODMN Discovery agent N.A. Investigative [1]
ISIS 134608 DMVX9IT Discovery agent N.A. Investigative [1]
ISIS 134499 DM90TOR Discovery agent N.A. Investigative [1]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Caspase 6 messenger RNA (CASP6 mRNA) TTKW4ML CASP6_HUMAN Not Available [1]

References

1 US patent application no. 6,566,135, Antisense modulation of caspase 6 expression.
2 Design, synthesis, and biological evaluation of isoquinoline-1,3,4-trione derivatives as potent caspase-3 inhibitors. J Med Chem. 2006 Mar 9;49(5):1613-23.
3 Synthesis and in vitro evaluation of sulfonamide isatin Michael acceptors as small molecule inhibitors of caspase-6. J Med Chem. 2009 Apr 23;52(8):2188-91.