Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMD6AUX)

Drug Name

Tat-NR2B9c Drug Info

Synonyms

NA-1; NA-1); PSD-95 inhibitor (stroke), NoNO/Arbor Vita; NMDAR NR2 domain-binding protein + HIV-1 Tat protein (Stroke), NoNO/Arbor Vita

Indication

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Presynaptic density protein 95 (DLG4)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
2-Methyl-2,4-Pentanediol	DMD45CU	Discovery agent	N.A.	Investigative	[3]
Guanosine-5'-Monophosphate	DM3SLZK	Discovery agent	N.A.	Investigative	[3]
KSG-YEKLSSIESDV	DMPLFRC	Discovery agent	N.A.	Investigative	[4]
N-(3,4-Difluorophenyl)propyl-ETAV	DMF2D4O	Discovery agent	N.A.	Investigative	[4]
N-Propyl-ETAV	DMUTDNV	Discovery agent	N.A.	Investigative	[4]
N-Phenylethyl-ETAV	DM1VSO9	Discovery agent	N.A.	Investigative	[4]
N-Cyclohexylmethyl-ETAV	DMIC8Z6	Discovery agent	N.A.	Investigative	[4]
FETAV	DMO1N2T	Discovery agent	N.A.	Investigative	[4]
N-Butyl-ETAV	DMY3HEF	Discovery agent	N.A.	Investigative	[4]
N-Methyl-ETAV	DMP1EF6	Discovery agent	N.A.	Investigative	[4]
------------------------------------------------------------------------------------


⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Presynaptic density protein 95 (DLG4)	TT9PB26	DLG4_HUMAN	Inhibitor	[1]

------------------------------------------------------------------------------------

References

1	Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain. Nature. 2012 Feb 29;483(7388):213-7.
2	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
4	Modified peptides as potent inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction. J Med Chem. 2008 Oct 23;51(20):6450-9.