Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMEBPCO)

Drug Name

SLG Drug Info

Synonyms

1-stearoyl-2-linoleoyl-sn-glycerol

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Short transient receptor potential channel 6 (TRPC6)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
2-APB	DM9AKVR	Discovery agent	N.A.	Investigative	[3]
lysophosphatidylcholine	DMOGFVH	Discovery agent	N.A.	Investigative	[3]
ACAA	DMACYPW	Discovery agent	N.A.	Investigative	[3]
OAG	DMOP8IJ	Discovery agent	N.A.	Investigative	[2]
KB-R7943	DMMD5W3	Discovery agent	N.A.	Investigative	[3]
flufenamate	DMN8AP0	Discovery agent	N.A.	Investigative	[3]
SAG	DMHOG7W	Discovery agent	N.A.	Investigative	[2]
ML9	DMP13VE	Discovery agent	N.A.	Investigative	[3]
hyp 9	DM0U8IV	Discovery agent	N.A.	Investigative	[4]
20-HETE	DM5BAJ9	Discovery agent	N.A.	Investigative	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Short transient receptor potential channel 6 (TRPC6)	TTRBT3W	TRPC6_HUMAN	Activator	[2]

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2442).
2	Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol. Nature. 1999 Jan 21;397(6716):259-63.
3	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 491).
4	Simple 2,4-diacylphloroglucinols as classic transient receptor potential-6 activators--identification of a novel pharmacophore. Mol Pharmacol. 2010 Mar;77(3):368-77.