Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMEKMV0)

Drug Name

9-(Ethoxyimino)-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile Drug Info

Synonyms

HY50737A; 924296-19-5; 9-(ethoxyimino)-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile; USP8-IN-22e; (9E)-9-ethoxyiminoindeno[1,2-b]pyrazine-2,3-dicarbonitrile; SCHEMBL1512635; 9-ethoxyiminoindeno[1,2-b]pyrazine-2,3-dicarbonitrile; 9-ethyloxyimino-9h-indeno[1,2-b]pyrazine-2,3-dicarbonitrile

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Preclinical	[1]

Cross-matching ID

PubChem CID: 73230796
TTD Drug ID: DMEKMV0

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Ubiquitin isopeptidase Y (USP8)	TT1J07C	UBP8_HUMAN	Inhibitor	[1]

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References

1	Synthesis and biological evaluation of 9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile analogues as potential inhibitors of deubiquitinating enzymes. ChemMedChem. 2010 Apr 6;5(4):552-8.