Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMEXW31)

Drug Name
NSC-663284 Drug Info
Synonyms
NSC 663284; 383907-43-5; NSC-663284; NSC663284; CDC25 Phosphatase Inhibitor II, NSC 663284; 6-Chloro-7-(2-morpholin-4-yl-ethylamino)quinoline-5,8-dione; 6-chloro-7-{[2-(morpholin-4-yl)ethyl]amino}quinoline-5,8-dione; DA3003-1; 6-Chloro-7-((2-morpholinoethyl)amino)quinoline-5,8-dione; AC1Q3HBF; AC1Q3HBE; SPS8I1; MLS006010693; SCHEMBL2556224; AC1L8E02; CTK4H9880; CHEBI:92053; DTXSID50327512; MolPort-003-983-788; HMS3268K22; BCP16027; MFCD08276924; BS0130; ZINC100002044; AKOS024456823; CS-7519; NCGC00092289-01; NCGC00092289-02
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
379077
ChEBI ID
CHEBI:92053
CAS Number
CAS 383907-43-5
TTD Drug ID
DMEXW31

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Discontinued Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting M-phase inducer phosphatase 3 (MPIP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
MX-7065 DMP26BW Solid tumour/cancer 2A00-2F9Z Terminated [2]
BN-82685 DMZME4N Discovery agent N.A. Investigative [1]
BN-82002 DMXY574 Solid tumour/cancer 2A00-2F9Z Investigative [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
M-phase inducer phosphatase 3 (MPIP3) TTESBNC MPIP3_HUMAN Inhibitor [1]

References

1 Synthesis and biological evaluation of novel heterocyclic quinones as inhibitors of the dual specificity protein phosphatase CDC25C. Bioorg Med Chem Lett. 2006 Jan 1;16(1):171-5.
2 Handbook of Assay Development in Drug Discovery, Lisa K. Minor, 2013. Page(11).
3 Synthesis of small molecule CDC25 phosphatases inhibitors. Bioorg Med Chem Lett. 2004 Dec 6;14(23):5809-12.