Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMF7EX8)

Drug Name

EGFR antisense DNA Drug Info

Synonyms

Antisense therapy, UPCI; EGFR antisense DNA, University of Pittsburgh

Indication

Disease Entry	ICD 11	Status	REF
Head and neck cancer	2D42	Phase 1/2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting EGFR messenger RNA (EGFR mRNA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
AC0010	DMQRL2Y	Non-small-cell lung cancer	2C25.Y	Phase 3	[3]
CK-101	DMMVWSY	Non-small-cell lung cancer	2C25.Y	Phase 1/2	[3]
Pyrotinib	DMW7K39	Solid tumour/cancer	2A00-2F9Z	Phase 1	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

References

1	ClinicalTrials.gov (NCT00903461) Safety and Efficacy of Radiation/Cetuximab Plus EGFR Antisense DNA for Head and Neck Squamous Cell Carcinoma. U.S. National Institutes of Health.
2	Antitumor Effects of EGFR Antisense Guanidine-Based Peptide Nucleic Acids in Cancer Models. ACS Chem Biol. 2013 February 15; 8(2): 345-352.
3	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)