Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMFBN9O)

Drug Name

BB-78484 Drug Info

Synonyms

SCHEMBL5482389

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Preclinical Drug(s)

Discontinued Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Pseudomonas UDP-3-O-acyl-GlcNAc deacetylase (Pseudo lpxC)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
LpxC-1	DMV1A25	Acinetobacter baumannii infection	CA40.0Y	Preclinical	[2]
RC-01	DM4FNWO	Gram-negative bacterial infection	1B74-1G40	Terminated	[3]
MYRISTIC ACID	DMYX0BL	Discovery agent	N.A.	Investigative	[4]
Cacodylate Ion	DMK4XLD	Discovery agent	N.A.	Investigative	[5]
Palmitoleic Acid	DM4W5X8	Discovery agent	N.A.	Investigative	[5]
3-(heptyloxy)benzoic acid	DMQZU9G	Discovery agent	N.A.	Investigative	[4]
BB-78485	DMJKA3F	Discovery agent	N.A.	Investigative	[1]
Tu-514	DMUR0TF	Discovery agent	N.A.	Investigative	[5]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Pseudomonas UDP-3-O-acyl-GlcNAc deacetylase (Pseudo lpxC)	TT0OFWN	LPXC_PSEAE	Inhibitor	[1]

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References

1	Antibacterial activities and characterization of novel inhibitors of LpxC. Antimicrob Agents Chemother. 2002 Jun;46(6):1793-9.
2	Different drugs for bad bugs: antivirulence strategies in the age of antibiotic resistance. Nat Rev Drug Discov. 2017 Jul;16(7):457-471.
3	The global preclinical antibacterial pipeline. Nat Rev Microbiol. 2020 May;18(5):275-285.
4	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
5	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.