Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMFP6MV)

Drug Name

Fidaxomicin Drug Info

Synonyms

Dificid (TN)

Indication

Disease Entry	ICD 11	Status	REF
Clostridioides difficile infection	1A04	Approved	[1]
Clostridium difficile associated diarrhea	1A04	Approved	[2]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Bacterial RNA polymerase switch region (Bact RNAP-SR)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Rifampin	DMA8J1G	Tuberculosis	1B10-1B1Z	Approved	[4]
Rifalazil	DMYXOHV	Bacterial infection	1A00-1C4Z	Phase 3	[5]
------------------------------------------------------------------------------------

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Bacterial RNA polymerase switch region (Bact RNAP-SR)	TTIJ5EB	NOUNIPROTAC	Modulator	[3]

------------------------------------------------------------------------------------

References

1	Fidaxomicin FDA Label
2	2011 FDA drug approvals. Nat Rev Drug Discov. 2012 Feb 1;11(2):91-4.
3	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
4	Bacillus subtilis tolerance of moderate concentrations of rifampin involves the sigma(B)-dependent general and multiple stress response. J Bacteriol. 2002 Jan;184(2):459-67.
5	Novel agents in the management of Mycobacterium tuberculosis disease. Curr Med Chem. 2007;14(18):2000-8.