Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMFTGHX)

Drug Name

Ad5CMV-NIS Drug Info

Synonyms

Sodium iodide symporter adenoviral gene therapy (prostate cancer); Sodium iodide symporter adenoviral gene therapy (prostate cancer), Mayo Clinic

Indication

Disease Entry	ICD 11	Status	REF
Prostate cancer	2C82.0	Phase 1	[1]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Sodium/iodide cotransporter (SLC5A5)	TTW7HI9	SC5A5_HUMAN	Modulator	[2]

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References

1	ClinicalTrials.gov (NCT00788307) Gene Therapy and Radioactive Iodine in Treating Patients With Locally Recurrent Prostate Cancer That Did Not Respond to External-Beam Radiation Therapy. U.S. NationalInstitutes of Health.
2	Noninvasive Imaging and Radiovirotherapy of Prostate Cancer Using an Oncolytic Measles Virus Expressing the Sodium Iodide Symporter. Mol Ther. 2009 December; 17(12): 2041-2048.