Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMGD0HT)

Drug Name

Tellurium Drug Info

Synonyms

Tellurium; 13494-80-9; Telloy; Tellur; Aurum paradoxum; Tellurium element; Tellur [Polish]; Metallum problematum; Tellurium, metallic; Tellurium, elemental; Tellurium Atom; UNII-NQA0O090ZJ; Tellurium and compounds; HSDB 2532; NCI-C60117; EINECS 236-813-4; NQA0O090ZJ; teluro; Tellurium, 99+%, (trace metal basis), powder; Tellurium, 99.999%, (trace metal basis), powder; tellure; Tellurium compounds, n.o.s.; Tellurium, 99.8%, (trace metal basis), powder, -200 mesh; Tellurium powder; Tellurium compounds; ACMC-1BQVR; 52Te; EC 236-813-4

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 6327182
ChEBI ID: CHEBI:30452
CAS Number: CAS 13494-80-9
TTD Drug ID: DMGD0HT

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Discontinued Drug(s)

Investigative Drug(s)

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Drug(s) Targeting Squalene monooxygenase (SQLE)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Naftifine	DMHVBG1	Dermatomycosis	EA60	Approved	[2]
Tolnaftate	DM28MU7	Dermatophytosis	1F28.2	Approved	[3]
Epigallocatechin gallate	DMCGWBJ	Hepatic fibrosis	DB93.0	Phase 3	[4]
FR-194738	DMNACIV	Hypercholesterolaemia	5C80.0	Terminated	[5]
SDZ-87-469	DMBY6CQ	Coronary artery disease	BA80	Terminated	[3]
NB-598	DMJVTQN	N. A.	N. A.	Terminated	[1]
ELLAGIC ACID	DMX8BS5	Discovery agent	N.A.	Investigative	[4]
1,2,3,4,6-penta-O-galloyl-beta-D-glucose	DMTK650	Discovery agent	N.A.	Investigative	[4]
Pedunculagin	DMKLRCX	Discovery agent	N.A.	Investigative	[4]
CORILAGIN	DMAC698	Discovery agent	N.A.	Investigative	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Squalene monooxygenase (SQLE)	TTE14XG	ERG1_HUMAN	Inhibitor	[1]

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References

1	Squalene epoxidase as hypocholesterolemic drug target revisited. Prog Lipid Res. 2003 Jan;42(1):37-50.
2	Characterization of squalene epoxidase activity from the dermatophyte Trichophyton rubrum and its inhibition by terbinafine and other antimycotic agents. Antimicrob Agents Chemother. 1996 Feb;40(2):443-7.
3	Effects of squalene epoxidase inhibitors on Candida albicans. Antimicrob Agents Chemother. 1992 Aug;36(8):1779-81.
4	Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase. J Nat Prod. 2001 Aug;64(8):1010-4.
5	Synthesis and biological activity of a novel squalene epoxidase inhibitor, FR194738. Bioorg Med Chem Lett. 2004 Feb 9;14(3):633-7.