Details of the Drug-Related molecule(s) Interaction Atlas

SC-47085 Drug Info

Olsalazine; Azodisal; Dipentium; Mirtazanine; Olsalazina; Olsalazina [Spanish]; Olsalazine (INN); Olsalazine [INN:BAN]; Olsalazinum; Olsalazinum [Latin]; Salicylic acid, 5,5'-azodi-; ULS5I8J03O; mordant yellow 5; (E)-5,5'-(diazene-1,2-diyl)bis(2-hydroxybenzoic acid); 15722-48-2; 3,3'-Azobis(6-hydroxybenzoic acid); 3,3'-diazene-1,2-diylbis(6-hydroxybenzoic acid); 5,5'-Azobis(salicylic acid); 5,5'-azodisalicylic acid; Benzoic acid, 3,3'-azobis(6-hydroxy-; C.I. Mordant Yellow 5; C14H10N2O6; CHEBI:7770; Rasal; UNII-ULS5I8J03O

Cross-matching ID

PubChem CID

22419

ChEBI ID

CHEBI:7770

CAS Number

CAS 15722-48-2

TTD Drug ID

DMGH4Q0

INTEDE Drug ID

DR2394

General Information of Drug (ID: DMGH4Q0)

Molecule-Related Drug Atlas

Molecule Type:

DME

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Discontinued Drug(s)

Investigative Drug(s)

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Drug(s) Metabolized By Azoreductase (azoR)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Balsalazide	DM7I1T9	Inflammatory bowel disease	DD72	Approved	[2]
CTK0H-9987	DMSGYNP	N. A.	N. A.	Phase 2	[3]
CB1954	DMVP4YK	Solid tumour/cancer	2A00-2F9Z	Discontinued in Phase 2	[4]
Ipsalazide	DMYEM59	N. A.	N. A.	Investigative	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug-Metabolizing Enzyme (DME)

References

1	Olsalazine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in inflammatory bowel disease. Drugs. 1991 Apr;41(4):647-64.
2	Studies of two novel sulfasalazine analogs, ipsalazide and balsalazide. Dig Dis Sci. 1983 Jul;28(7):609-15.
3	The role of the gut flora in the metabolism of prontosil and neoprontosil in the rat. Xenobiotica. 1971 Mar;1(2):143-56.
4	Discovery and evaluation of Escherichia coli nitroreductases that activate the anti-cancer prodrug CB1954. Biochem Pharmacol. 2010 Mar 1;79(5):678-87.