Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMGIN7J)

Drug Name

Onyvax-105 Drug Info

Synonyms

Antibody therapy (colerectal cancer), CRC/Onyvax; Vaccine (colorectal cancer), CRC/ImClone; Vaccine (colorectal cancer), CRC/Onyvax

Indication

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Complement decay-accelerating factor (CD55)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Coxsackievirus A21	DM2K5VP	Glioblastoma multiforme	2A00.0	Phase 2	[4]
PAT-SC1	DMZKFJO	Gastric adenocarcinoma	2B72	Phase 1/2	[5]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Complement decay-accelerating factor (CD55)	TT5Z9WY	DAF_HUMAN	Not Available	[3]

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References

1	Onyvax-105 Cancer Vaccine Shows Encouraging Clinical Results in Osteosarcoma Patients After Intensive Chemotherapy. Onyvax vaccines therapies. April 19, 2005.
2	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006889)
3	Technology evaluation: Onyvax-105, Onyvax. Curr Opin Mol Ther. 2003 Dec;5(6):668-72.
4	Oncolytic Coxsackievirus A21 as a novel therapy for multiple myeloma. Br J Haematol. 2007 Apr;137(2):133-41.
5	Ten-year follow-up of a prospective trial for the targeted therapy of gastric cancer with the human monoclonal antibody PAT-SC1. Oncol Rep. 2014 Mar;31(3):1059-66.