Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMGINBT)

Drug Name
SGC707 Drug Info
Synonyms
1687736-54-4; SGC 707; SGC-707; 1-Isoquinolin-6-Yl-3-[2-Oxo-2-(Pyrrolidin-1-Yl)ethyl]urea; GTPL8552; KS-00000THM; AOB5757; MolPort-039-101-300; EX-A1304; BCP16746; s7832; ZINC220951188; AKOS025142099; CS-5370; ACN-053041; NCGC00384204-04; HY-19715; AK546586; SGC707, > AS-16917; FT-0700238; J-690235; 1-isoquinolin-6-yl-3-(2-oxo-2-pyrrolidin-1-ylethyl)urea; 1-(isoquinolin-6-yl)-3-[2-oxo-2-(pyrrolidin-1-yl)ethyl]urea; 1-(Isoquinolin-6-yl)-3-[2-oxo-2-(pyrrolidin-1-yl)ethyl] urea
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
90642938
ChEBI ID
CHEMBL4072005
TTD Drug ID
DMGINBT

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Protein arginine methyltransferase 3 (PRMT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
PMID22795084C1 DM0XQZO Discovery agent N.A. Investigative [2]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Protein arginine methyltransferase 3 (PRMT3) TTL4XSQ ANM3_HUMAN Modulator (allosteric modulator) [1]

References

1 A potent, selective and cell-active allosteric inhibitor of protein arginine methyltransferase (PRMT3). Angew Chem Int Ed Engl. 2015 Apr 20;54(17):5166-70.
2 An allosteric inhibitor of protein arginine methyltransferase 3. Structure. 2012 Aug 8;20(8):1425-35.