Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMGLQ72)

Drug Name

[14C]GlySar Drug Info

Synonyms

[14C]-GlySar; glycylsarcosine

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Solute carrier family 15 member 2 (SLC15A2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Lys[Z(NO2)]-Pro	DMJX4GA	Discovery agent	N.A.	Investigative	[3]
[11C]GlySar	DM5Q08F	Discovery agent	N.A.	Investigative	[3]
[3H]GlySar	DMFEYLS	Discovery agent	N.A.	Investigative	[3]
Lys[Z(NO2)]-Lys[Z(NO2)]	DMH0Q9V	Discovery agent	N.A.	Investigative	[4]
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Drug(s) Targeting Solute carrier family 15 member 1 (SLC15A1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Lys[Z(NO2)]-Pro	DMJX4GA	Discovery agent	N.A.	Investigative	[5]
[11C]GlySar	DM5Q08F	Discovery agent	N.A.	Investigative	[2]
[3H]GlySar	DMFEYLS	Discovery agent	N.A.	Investigative	[2]
4-AMBA	DMYNASR	Discovery agent	N.A.	Investigative	[6]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Solute carrier family 15 member 1 (SLC15A1)	TT5LF3C	S15A1_HUMAN	Modulator	[2]
Solute carrier family 15 member 2 (SLC15A2)	TT27Q3A	S15A2_HUMAN	Modulator	[3]

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4599).
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 984).
3	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 985).
4	Defining minimal structural features in substrates of the H(+)/peptide cotransporter PEPT2 using novel amino acid and dipeptide derivatives. Mol Pharmacol. 2002 Jan;61(1):214-21.
5	A novel inhibitor of the mammalian peptide transporter PEPT1. Biochemistry. 2001 Apr 10;40(14):4454-8.
6	Activation of vagal afferents in the rat duodenum by protein digests requires PepT1. J Nutr. 2005 Jun;135(6):1491-5.