Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMGNHC2)

Drug Name

MK-3415A Drug Info

Synonyms

Actoxumab/bezlotoxumab

Indication

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

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Drug(s) Targeting Clostridium difficile Toxin B (CD toxB)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Bezlotoxumab	DMTZC5G	C. difficile infection	1A04	Approved	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Clostridium difficile Toxin A (CD toxA)	TT64H8L	TOXA_CLODI	Not Available	[1]
Clostridium difficile Toxin B (CD toxB)	TTQH65V	TOXB_CLODI	Not Available	[1]

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References

1	ClinicalTrials.gov (NCT01513239) A Study of MK-6072 and MK-3415A in Participants Receiving Antibiotic Therapy for Clostridium Difficile Infection (MK-3415A-002). U.S. National Institutes of Health.
2	2016 FDA drug approvals. Nat Rev Drug Discov. 2017 Feb 2;16(2):73-76.