Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMGUM90)

Drug Name

Anti-CD133-CAR vector-transduced T cells Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Brain cancer	2A00	Phase 1	[1]
Colorectal cancer	2B91.Z	Phase 1	[1]
Liver cancer	2C12	Phase 1	[1]
Ovarian cancer	2C73	Phase 1	[1]
Pancreatic cancer	2C10	Phase 1	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Preclinical Drug(s)

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Drug(s) Targeting Prominin-1 (PROM1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ICT-121	DM64LVS	Recurrent glioblastoma	2A00.00	Phase 1	[2]
CAR-T cells targeting CD133	DMYOR5T	Acute myeloid leukaemia	2A60	Preclinical	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	ClinicalTrials.gov (NCT02541370) Treatment of Relapsed and/or Chemotherapy Refractory Advanced Malignancies by CART133
2	Immunotargeting of cancer stem cells. Contemp Oncol (Pozn) 2015; 19(1A): A52-A59.
3	ClinicalTrials.gov (NCT03473457) CAR-T Cells Therapy in Relapsed/Refractory Acute Myeloid Leukemia