Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMGZ3DR)

Drug Name
NT-3 Drug Info
Synonyms Neurotrophin-3; NT-3, Amgen-Regeneron Partners; NT-3, Amgen/ Regeneron; Neurotrophin-3, Amgen-Regeneron Partners; Neurotrophin-3, Amgen/ Regeneron
Indication
Disease Entry ICD 11 Status REF
Constipation DD91.1 Discontinued in Phase 2 [1]
Cross-matching ID
TTD Drug ID
DMGZ3DR

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Discontinued Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Neurotrophin-3 (NTF3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
ReN-1826 DMGY51F Central nervous system disease 8A04-8D87 Terminated [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Neurotrophin-3 (NTF3) TTZHKV9 NTF3_HUMAN Modulator [2]

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5033).
2 NT-3. Takeda/Regeneron/Amgen. IDrugs. 2001 Jul;4(7):820-4.
3 Pulmonary distribution, regulation, and functional role of Trk receptors in a murine model of asthma. J Allergy Clin Immunol. 2006 Sep;118(3):597-605.