Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMHRY8A)

Drug Name
THR-687 Drug Info
Indication
Disease Entry ICD 11 Status REF
Diabetic macular edema 9B71.02 Phase 1 [1]
Diabetic retinopathy 9B71.0 Phase 1 [1]
Cross-matching ID
TTD Drug ID
DMHRY8A

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Integrin (ITG) TTQFP08 NOUNIPROTAC Antagonist [2]

References

1 ClinicalTrials.gov (NCT03666923) A Study to Evaluate the Safety of THR-687 in Subjects With Diabetic Macular Edema (DME). U.S. National Institutes of Health.
2 The potent small molecule integrin antagonist THR-687 is a promising next-generation therapy for retinal vascular disorders. Exp Eye Res. 2019 Mar;180:43-52.