Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMHWN63)

Drug Name

TEV-48574 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Crohn disease	DD70	Phase 2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Vascular endothelial cell growth inhibitor (TNFSF15)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
PRA023	DMUY4VV	Crohn disease	DD70	Phase 2	[3]
PF-07261271	DM0K4WQ	Inflammatory bowel disease	DD72	Phase 1	[4]
------------------------------------------------------------------------------------

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Vascular endothelial cell growth inhibitor (TNFSF15)	TTEST6I	TNF15_HUMAN	Not Available	[2]

------------------------------------------------------------------------------------

References

1	ClinicalTrials.gov (NCT05668013) A 44-Week Phase 2b Long-Term Extension, RandomizEd, Double-BLind, Study to Determine the Long-Term PharmacokInetics, Efficacy, Safety, and Tolerability of TEV-48574 in Adult PatiEnts With Moderate to Severe Ulcerative Colitis or Crohn's Disease Who Completed the Main Phase of the Dose-Ranging Study (RELIEVE UCCD LTE). U.S.National Institutes of Health.
2	Clinical pipeline report, company report or official report of Teva Pharmaceutical
3	Clinical pipeline report, company report or official report of Prometheus Biosciences
4	Clinical pipeline report, company report or official report of Pfizer