General Information of Drug (ID: DMI3YLK)

Drug Name
LA-EP2006 Drug Info
Indication
Disease Entry ICD 11 Status REF
Neutropenia 4B00.0 Phase 3 [1]
Cross-matching ID
TTD Drug ID
DMI3YLK

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Eflapegrastim DMACVEI Neutropenia 4B00.0 Approved [3]
Efbemalenograstim DMDNJ18 Neutropenia 4B00.0 Approved [4]
Interleukin-3 DM1Y69Q Aplastic anemia 3A70 Approved [5]
Neugranin DMLRKJX Neutropenia 4B00.0 Preregistration [6]
DA-3031 DM6S4R2 Neutropenia 4B00.0 Phase 3 [7]
MK-4214 DMA25NO Neutropenia 4B00.0 Phase 3 [8]
⏷ Show the Full List of 6 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Granulocyte colony-stimulating factor (CSF3) TT5TQ2W CSF3_HUMAN Modulator [2]

References

1 ClinicalTrials.gov (NCT01516736) Phase III Study Comparing the Efficacy and Safety of LA-EP2006 and Peg-Filgrastim. U.S. National Institutes of Health.
2 National Cancer Institute Drug Dictionary (drug id 724518).
3 Company report (Sppirx)
4 Clinical pipeline report, company report or official report of Generon (Shanghai) Corporation Ltd.
5 Interleukin 3: from colony-stimulating factor to pluripotent immunoregulatory cytokine. Int J Immunopharmacol. 1992 Apr;14(3):421-30.
6 Development and Characterization of a Novel Fusion Protein of a Mutated Granulocyte Colony-Stimulating Factor and Human Serum Albumin in Pichia pastoris. PLoS One. 2014; 9(12): e115840.
7 A randomized, multi-center, open-label, phase II study of once-per-cycle DA-3031, a biosimilar pegylated G-CSF, compared with daily filgrastim in patients receiving TAC chemotherapy for early-stage breast cancer.Invest New Drugs.2013 Oct;31(5):1300-6.
8 DOI: 10.1038/nbt0710-636a