Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMIUX3D)

Drug Name

Methyl aminolevulinate Drug Info

Synonyms

Metvix; Aminolevulinic acid methyl ester; Methyl 5-aminolevulinate; Methyl delta-aminolevulinate; Methyl5-amino-4-oxopentanoate; Levulinic acid, 5-amino-, methyl ester; Pentanoic acid, 5-amino-4-oxo-, methyl ester; 5-Aminolevulinic acid methyl ester

Indication

Disease Entry	ICD 11	Status	REF
Acne vulgaris	ED80	Approved	[1]

Therapeutic Class

Anticancer Agents

Cross-matching ID

PubChem CID: 157922
ChEBI ID: CHEMBL724125
CAS Number: CAS 33320-16-0
TTD Drug ID: DMIUX3D

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Ferrochelatase (FECH)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cholic Acid	DM7OKQV	Cholelithiasis	DC11	Approved	[3]
N-Methylmesoporphyrin Containing Copper	DMKZL5H	Discovery agent	N.A.	Investigative	[3]
Lead acetate	DML0GZ2	Discovery agent	N.A.	Investigative	[4]
N-Methylmesoporphyrin	DM4FMZP	Discovery agent	N.A.	Investigative	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Ferrochelatase (FECH)	TTQ6VF4	HEMH_HUMAN	Activator	[2]

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References

1	FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 021415.
2	Low-dose methotrexate enhances aminolevulinate-based photodynamic therapy in skin carcinoma cells in vitro and in vivo. Clin Cancer Res. 2009 May 15;15(10):3333-43.
3	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
4	Ferrochelatase, a novel target for photodynamic therapy of cancer. Oncol Rep. 1999 Nov-Dec;6(6):1439-42.