Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMJ2ZFV)

Drug Name

EB-1053 Drug Info

Synonyms

EB 1053; 125946-92-1; Disodium 1-hydroxy-3-(1-pyrrolidinyl)propylidene-1,1-bisphosphonate; AC1L2Y2V; SCHEMBL3067217; DTXSID20154998; Phosphonic acid, (1-hydroxy-3-(1-pyrrolidinyl)propylidene)bis-, disodium salt; disodium (1-hydroxy-1-phosphonato-3-pyrrolidin-1-ylpropyl)phosphonic acid

Indication

Disease Entry	ICD 11	Status	REF
Osteoporosis	FB83.0	Discontinued in Phase 2	[1]

Cross-matching ID

PubChem CID: 130822
CAS Number: CAS 125946-92-1
TTD Drug ID: DMJ2ZFV

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Bone resorption factor (BRF)	TTKOBY0	IBP1_HUMAN; IBP2_HUMAN; IBP3_HUMAN	Modulator	[2]

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References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006406)
2	Disodium 1-hydroxy-3-(1-pyrrolidinyl)-propylidene-1,1-bisphosphonate (EB-1053) is a potent inhibitor of bone resorption in vitro and in vivo. J Bone Miner Res. 1992 Aug;7(8):981-6.